Document Type

Report

Publication Date

8-2014

Abstract

Genomic instability is an important factor in cancer induced by ionizing radiation. Global DNA hypomethylation has been recently proposed as a potential biomarker for cancer risk through genomic instability. However the association between low-dose ionizing radiation exposure and DNA methylation changes is unclear. This study aimed to understand the epigenetic mechanisms associated with low-level radiation exposure and radiation-induced genomic instability (RIGI) among industrial radiographers.

Rights

© 2014 Yoon Hee Cho

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