Genomic instability is an important factor in cancer induced by ionizing radiation. Global DNA hypomethylation has been recently proposed as a potential biomarker for cancer risk through genomic instability. However the association between low-dose ionizing radiation exposure and DNA methylation changes is unclear. This study aimed to understand the epigenetic mechanisms associated with low-level radiation exposure and radiation-induced genomic instability (RIGI) among industrial radiographers.
© 2014 Yoon Hee Cho
Cho, Yoon Hee, "Radiation-induced genomic instability and LINE-1 hypomethylation in radiographers" (2014). University Grant Program Reports. 1.