Document Type
Article
Publication Title
Current Opinion in Structural Biology
Publication Date
1993
Volume
3
Issue
6
Disciplines
Biology | Life Sciences
Abstract
Seven discrete families of cytokines have been identified by sequence and structural analysis. Within this diverse set of protein folds, the hematopoietic growth factors and tumor necrosis factor-like cytokines display a remarkable degree of variation upon their respective topological frameworks. In addition, prototype X-ray structures of ligand-receptor complexes reveal two different strategies of receptor engagement.
DOI
https://doi.org/10.1016/0959-440X(93)90144-A
Rights
© Current Biology Ltd
Recommended Citation
Sprang, Stephen R. and Fernando Bazan, J., "Cytokine structural taxonomy and mechanisms of receptor engagement" (1993). Biological Sciences Faculty Publications. 551.
https://scholarworks.umt.edu/biosci_pubs/551