Poster Session #2: UC South Ballroom
Auditory evoked potentials in humans and laboratory rats
Presentation Type
Poster
Faculty Mentor’s Full Name
Al Yonovitz
Abstract / Artist's Statement
Evoked potentials provide a basis for the objective analysis of the auditory system. An animal model of hearing is very useful for studying untoward effects of drug therapy, toxic substances and noise-induced hearing loss. The Auditory Brainstem Response (ABR) can be recorded using surface electrodes from lower animals and humans. The morphology of the ABR has been shown to correlate well with structures of the auditory pathway. This research compares the results of the human ABR with that of rat responses. A specially designed software program allowed concurrent ABR responses. This program will be discussed as well as the method for obtaining rat ABR’s. The concurrent responses were designed to provide a reliability index that was utilized to improve the determination of auditory thresholds. The stimuli were pure tones with a Blackman envelope. The Blackman envelope provides a minimal amount of spurious signals for brief stimuli (2 msec). A complete auditory threshold for all octave frequencies can be obtained in less than one hour.
Category
Life Sciences
Auditory evoked potentials in humans and laboratory rats
Evoked potentials provide a basis for the objective analysis of the auditory system. An animal model of hearing is very useful for studying untoward effects of drug therapy, toxic substances and noise-induced hearing loss. The Auditory Brainstem Response (ABR) can be recorded using surface electrodes from lower animals and humans. The morphology of the ABR has been shown to correlate well with structures of the auditory pathway. This research compares the results of the human ABR with that of rat responses. A specially designed software program allowed concurrent ABR responses. This program will be discussed as well as the method for obtaining rat ABR’s. The concurrent responses were designed to provide a reliability index that was utilized to improve the determination of auditory thresholds. The stimuli were pure tones with a Blackman envelope. The Blackman envelope provides a minimal amount of spurious signals for brief stimuli (2 msec). A complete auditory threshold for all octave frequencies can be obtained in less than one hour.