Poster Session II
Project Type
Poster - Campus Access Only
Project Funding and Affiliations
Supported by the United States Department of Defense, Department of the Air Force (FA8650-19-C6124), Cardiopulmonary and Cancer Rehabilitation Laboratory, Montana Center for Work Physiology and Exercise Metabolism
Faculty Mentor’s Full Name
John Quindry
Faculty Mentor’s Department
School of Integrative Physiology and Athletic Training
Additional Mentor
Ron Michalak (ron.michalak@umconnect.umt.edu), Amanda Alfarochaverri (amanda.alfarochaverri@umconnect.umt.edu)
Abstract / Artist's Statement
Ava Lamers, Keiana Griggs, Ronald E Michalak, Amanda Alfaro-Chaverri, Mariam Rojas-Ledezma, Kenzie Williams, Alejandro M Rosales, Brent C Ruby, Dustin R Slivka, and John C Quindry
The current study analyzes select circulating blood biomarkers collected from females and males in a thermoregulatory heat acclimation protocol designed to simulate occupational work environments. Females and males (n=30 each) were randomly assigned into sub-groups (n=15 each) that performed 7 consecutive days of either sustained (90 minutes) or intermittent (3x30 minutes, 3-hour separation) low-to-moderate-intensity exercise in a hot laboratory-controlled environment (38°C, 60% RH). Biomarker assays quantified 46 selected cytokines from blood samples drawn on days 1 and 7, Pre- and Post the first 30 minutes of exercise. Statistically significant results for Interleukin (IL)-15, IL-6, IL-8, IL-1ra, and IL-10 were observed and compared with existing literature. Overall, other than isolated changes in a handful of cytokines, no clear pattern of inflammation was observed from the biomarkers examined. Although one sex-based difference was observed, overall findings provide limited evidence of meaningful differences in the five biomarker responses between females and males in low-to-moderate exercise in a heat-stress environment. Given the limited research on females in physiologically demanding occupations, sex-specific inflammatory responses to occupational work stress remain poorly understood relative to males.
Category
Physical Sciences
Cytokine Responses to Heat Acclimation during Occupational Exercise
UC South Ballroom
Ava Lamers, Keiana Griggs, Ronald E Michalak, Amanda Alfaro-Chaverri, Mariam Rojas-Ledezma, Kenzie Williams, Alejandro M Rosales, Brent C Ruby, Dustin R Slivka, and John C Quindry
The current study analyzes select circulating blood biomarkers collected from females and males in a thermoregulatory heat acclimation protocol designed to simulate occupational work environments. Females and males (n=30 each) were randomly assigned into sub-groups (n=15 each) that performed 7 consecutive days of either sustained (90 minutes) or intermittent (3x30 minutes, 3-hour separation) low-to-moderate-intensity exercise in a hot laboratory-controlled environment (38°C, 60% RH). Biomarker assays quantified 46 selected cytokines from blood samples drawn on days 1 and 7, Pre- and Post the first 30 minutes of exercise. Statistically significant results for Interleukin (IL)-15, IL-6, IL-8, IL-1ra, and IL-10 were observed and compared with existing literature. Overall, other than isolated changes in a handful of cytokines, no clear pattern of inflammation was observed from the biomarkers examined. Although one sex-based difference was observed, overall findings provide limited evidence of meaningful differences in the five biomarker responses between females and males in low-to-moderate exercise in a heat-stress environment. Given the limited research on females in physiologically demanding occupations, sex-specific inflammatory responses to occupational work stress remain poorly understood relative to males.