Document Type

Article

Publication Title

The Journal of Neuroscience

Publisher

Society for Neuroscience

Publication Date

2-5-2014

Abstract

Adult-generated granule cells (GCs) in the dentate gyrus must establish synapses with preexisting neurons to participate in network activity. To determine the source of early glutamatergic synapses on newborn GCs in adult mice, we examined synaptic currents at the developmental stage when NMDA receptor-mediated silent synapses are first established. We show that hilar mossy cells provide initial glutamatergic synapses as well as disynaptic GABAergic input to adult-generated dentate GCs.

DOI

10.1523/JNEUROSCI.3620-13.2014

Comments

Publisher's Version: http://www.jneurosci.org/content/34/6/2349.short

Rights

© 2014 the authors

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