Submissions from 2021
Leucine Carboxyl Methyltransferase 1 Overexpression Protects Against Cognitive and Electrophysiological Impairments in Tg2576 APP Transgenic Mice, Madhumathi Gnanaprakash, Agnieszka Staniszewski, Hong Zhang, Rose Pitstick, Michael P. Kavanaugh, Ottavio Arancio, and Russell E. Nicholls
Supplemental Ascorbate Diminishes DNA Damage Yet Depletes Glutathione and Increases Acute Liver Failure in a Mouse Model of Hepatic Antioxidant System Disruption, Colin G. Miller, Jean A. Kundert, Justin R. Prigge, Julie A. Amato, Allison E. Perez, Lucia Coppo, Gabrielle N. Rizzo, Michael P. Kavanaugh, David J. Orlicky, Colin T. Shearn, and Edward E. Schmidt
Submissions from 2020
Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints, Eric Vallabh Minikel, Hien T. Zhao, Jason Le, Jill O'Moore, Rose Pitstick, Samantha Graffam, George A. Carlson, and Michael P. Kavanaugh
Reduced Expression of the PP2A Methylesterase, PME-1, or the PP2A Methyltransferase, LCMT-1, Alters Sensitivity to Beta-Amyloid-Induced Cognitive and Electrophysiological Impairments in Mice, Agnieszka Staniszewski, Hong Zhang, Kesava Asam, Rose Pitstick, Michael P. Kavanaugh, Ottavio Arancio, and Russell E. Nicholls
Submissions from 2019
MODELING OF EXCITATORY AMINO ACID TRANSPORTERS AND CLEARANCE OF SYNAPTIC CLEFT ON MILLISECOND TIME SCALE, Denis M. Shchepakin, Leonid Kalachev, and Michael Kavanaugh
Submissions from 2016
D-Serine Is a Substrate for Neutral Amino Acid Transporters ASCT1/SLC1A4 and ASCT2/SLC1A5, and Is Transported by Both Subtypes in Rat Hippocampal Astrocyte Cultures, Alan C. Foster, Jill Farnsworth, Genevieve Lind, Yong-Xin Lin, Jia-Ying Yang, Van Dang, Mahmud Penjwini, Veena Viswanath, Ursula Staubli, and Michael Kavanaugh
MODELING OF AMBIENT GLUTAMATE CONCENTRATION MEASUREMENT IN THE MAMMALIAN NERVOUS SYSTEM, Denis M. Shchepakin, Michael Kavanaugh, and Leonid Kalachev
Submissions from 2015
Dendritic distributions of lh channels in experimentally-derived multi-compartment models of oriens-lacunosum/moleculare (O-LM) hippocampal interneurons, Vladislav Sekulic, Tse-Chiang Chen, J. Josh Lawrence, and Frances K. Skinner
Temporal and Spatial Changes in the Pattern of Iba1 and CD68 Staining in the Rat Brain Following Severe Traumatic Brain Injury, Debbie Smith, Diane Brooks, Eric Wohlgehagen, Thomas Rau, and David Poulsen
Submissions from 2014
Hilar Mossy Cells Provide the First Glutamatergic Synapses to Adult-Born Dentate Granule Cells, Jessica H. Chancey, David J. Poulsen, Jacques I. Wadiche, and Linda Overstreet-Wadiche
Radiation-induced genomic instability and LINE-1 hypomethylation in radiographers, Yoon Hee Cho
The Effect of Size on Ag Nanosphere Toxicity in Macrophage Cell Models and Lung Epithelial Cell Lines Is Dependent on Particle Dissolution, Raymond F. Hamilton, Sarah Buckingham, and Andrij Holian
Synthesis, characterization, and bioactivity of carboxylic acid-functionalized titanium dioxide nanobelts, Raymond F. Hamilton, Nianqiang Wu, Chengcheng Xiang, Ming Li, Feng Yang, Michael Wolfarth, Dale W. Porter, and Andrij Holian
Phenoxybenzamine Is Neuroprotective in a Rat Model of Severe Traumatic Brain Injury, Thomas Rau, Aakriti Kothiwal, Annela Rova, Joseph F. Rhoderick, and David J. Poulsen
Using Multi-Compartment Ensemble Modeling as an Investigative Tool of Spatially Distributed Biophysical Balances: Application to Hippocampal Oriens-Lacunosum/Moleculare (O-LM) Cellns, Vladislav Sekulic, J. Josh Lawrence, and Frances K. Skinner
Glutamate transporter control of ambient glutamate levels, Weinan Sun, Denis M. Shchepakin, Leonid Kalachev, and Michael P. Kavanaugh
Household reporting of childhood respiratory health and air pollution in rural Alaska Native communities, Desirae N. Ware, Johnnye Lewis, Scarlett Hopkins, Bert Boyer, Luke Montrose, Curis W. Noonan, Erin O. Semmens, and Tony J. Ward
Submissions from 2013
Brain immune interactions and air pollution: macrophage inhibitory factor (MIF), prion cellular protein (PrPC), Interleukin-6 (IL-6), interleukin 1 receptor antagonist (IL-1Ra), and interleukin-2 (IL-2) in cerebrospinal fluid and MIF in serum differentiate urban children exposed to severe vs. low air pollution, Lilian Calderón-Garcidueñas, Janet V. Cross, Maricela Franco-Lira, Mariana Aragón-Flores, Michael Kavanaugh, Ricardo Torres-Jardon, Chih-Kai Chao, Charles Thompson, Jing Chang, Hongtu Zhu, and Amedeo D'Angiulli
Early Alzheimer's and Parkinson's Disease Pathology in Urban Children: Friend versus Foe Responses—It Is Time to Face the Evidence, Lilian Calderón-Garcidueñas, Maricela Franco-Lira, Antonieta Mora-Tiscareño, Humberto Medina-Cortina, Ricardo Torres-Jardon, and Michael Kavanaugh
Exposure to Urban Air Pollution and Bone Health in Clinically Healthy Six-year-old Children, Lilian Calderón-Garcidueñas, Antonieta Mora-Tiscareño, Maricela Franco-Lira, Ricardo Torres-Jardon, Bernardo Pena-Cruz, Carolina Palacios-López, Hongtu Zhu, Linglong Kong, Nicolas Mendoza-Mendoza, Hortencia Montesinoscorrea, Lina Romero, Gildardo Valencia-Salazar, Michael Kavanaugh, and Silvestre Frenk
MRI of Neuronal Recovery After Low-Dose Methamphetamine Treatment of Traumatic Brain Injury in Rats, Guang Liang Ding, Michael Chopp, David J. Poulsen, Lian Li, Changsheng Qu, Qingjiang Li, Siamak P. Nejad-Davarani, John S. Budaj, Hongtao Wu, Asim Mahmood, and Quan Jiang
Analgesic Effect of a Mixed T-Type Channel Inhibitor/CB2 Receptor Agonist, Vinicius M. Gadotti, Haitao You, Ravil R. Petrov, N. Daniel Berger, Philippe Diaz, and Gerald W. Zamponi
Novel dicarboxylate selectivity in an insect glutamate transporter homolog, Hui Wang, Avi M. Rascoe, David Charles Holley, Eric Gouaux, and Michael Kavanaugh
Submissions from 2012
Single mutation to a sex pheromone receptor provides adaptive specificity between closely related moth species, Gregory Patrick Leary, Jean E. Allen, Peggy L. Bunger, Jena B. Luginbill, Charles E. Linn Jr., Irene E. Macallister, Michael Kavanaugh, and Kevin W. Wanner
Oxygen Glucose Deprivation in Rat Hippocampal Slice Cultures Results in Alterations in Carnitine Homeostasis and Mitochondrial Dysfunction, Thomas Rau, Qing Lu, Shruti Sharma, Xutong Sun, Gregory Leary, Matthew L. Beckman, Yal Hou, Mark S. Wainwright, Michael P. Kavanaugh, David J. Poulsen, and Stephen M. Black
Identifying Neurotransmitter Spill-over in Hippocampal Field Recordings, Emily Stone, Katie Hoffman, and Michael P. Kavanaugh
Submissions from 2011
From Good Intentions to Proven Interventions: Effectiveness of Actions to Reduce the Health Impacts of Air Pollution, Luisa V. Giles, Prabjit Barn, Nino Kuenzli, Isabelle Romieu, Murray A. Mittleman, Stephan van Eeden, Ryan Allen, Chris Carlsten, Dave Stieb, Curtis W. Noonan, Audrey Smargiassi, Joel D. Kaufman, Shakoor Hajat, Tom Kosatsky, and Michael Brauer
The central cavity in trimeric glutamate transporters restricts ligand diffusion, Gregory Patrick Leary, David Charles Holley, Emily F. Stone, Brent Russell Lyda, Leonid Kalachev, and Michael Kavanaugh
Specificity and Actions of an Arylaspartate Inhibitor of Glutamate Transport at the Schaffer Collateral-CA1 Pyramidal Cell Synapse, Weinan Sun, Katie Hoffman, David C. Holley, and Michael P. Kavanaugh
Specificity and Actions of an Arylaspartate Inhibitor of Glutamate Transport at the Schaffer Collateral-Ca1 Pyramidal Cell Synapse, Weinan Sun, Katie M. Hoffman, David C. Holley, and Michael P. Kavanaugh
Functional Characterization and Analgesic Effects of Mixed Cannabinoid Receptor/T-Type Channel Ligands, Haitao You, Vinicius M. Gadotti, Ravil R. Petrov, Gerald W. Zamponi, and Philippe Diaz
Submissions from 2010
Organophosphorus Pesticides Decrease M2 Muscarinic Receptor Function in Guinea Pig Airway Nerves Via Indirect Mechanisms, Becky J. Proskocil, Donald A. Bruun, Charles M. Thompson, Allison D. Fryer, and Pamela J. Lein
Mass Spectrometric Analyses of Organophosphate Insecticide Oxon Protein Adducts, Charles M. Thompson, John M. Prins, and Kathleen M. George
Submissions from 2009
Assembly of Arenavirus Envelope Glycoprotein Gpc in Detergent-Soluble Membrane Microdomains, Sudhakar S. Agnihothram, Brooke Dancho, Kenneth W. Grant, Mark L. Grimes, Douglas S. Lyles, and Jack H. Nunberg
Interactions of alkali cations with glutamate transporters, David C. Holley and Michael P. Kavanaugh
Urinary Levoglucosan as a Biomarker of Wood Smoke Exposure: Observations in a Mouse Model and in Children, Christopher T. Migliaccio, M. A. Bergauff, Christopher P. Palmer, Forrest Jessop, Curtis W. Noonan, and Tony Ward
Submissions from 2008
Neurovirulence of Polytropic Murine Retrovirus Is Influenced by Two Separate Regions on Opposite Sides of the Envelope Protein Receptor Binding Domain, Karin E. Peterson, Susan Pourciau, Min Du, Rachel LaCasse, Melissa Pathmajeyan, David J. Poulsen, Mavis Agbandje-McKenna, Kathy Wehrly, and Bruce Chesebro
Submissions from 2007
The Glutamate and Chloride Permeation Pathways Are Colocalized in Individual Neuronal Glutamate Transporter Subunits, Gregory Patrick Leary, Emily F. Stone, David Charles Holley, and Michael Kavanaugh
Submissions from 2006
APPL1 Associates with TrkA and GIPC1 and is Required for Nerve Growth Factor-Mediated Signal Transduction, D. C. Lin, C. Quevedo, N. E. Brewer, A. Bell, J. R. Testa, Mark L. Grimes, F. D. Miller, and D. R. Kaplan
Nested Case-Control Study of Autoimmune Disease in an Asbestos-Exposed Population, Curis W. Noonan, Jean C. Pfau, Theodore C. Larson, and Michael R. Spence
Submissions from 2005
Assessment of Autoimmune Responses Associated with Asbestos Exposure in Libby, Montana, USA, Jean C. Pfau, J. J. Sentissi, G. Weller, and Elizabeth Putnam
Submissions from 2004
Fluorometric measurements of conformational changes in glutamate transporters, H. Peter Larsson, Anastassios V. Tzingounis, Hans-Peter Koch, and Michael Kavanaugh
Submissions from 2003
Equilibrative Nucleoside Transporter Family Members from Leishmania donovani Are Electrogenic Proton Symporters, Alex Stein, Gayatri Vaseduvan, Nicola S. Carter, Buddy Ullman, Scott M. Landfear, and Michael Kavanaugh
Submissions from 2002
Dynamic Equilibrium between Coupled and Uncoupled Modes of a Neuronal Glutamate Transporter, Lars Borre, Michael Kavanaugh, and Baruch I. Kanner
Glutamine Uptake by Neurons: Interaction of Protons with System A Transporters, Farrukh A. Chaudhry, Dietmar Schmitz, Richard J. Reimer, Peter Larsson, Andrew T. Gray, Roger Nicoll, Michael Kavanaugh, and Robert H. Edwards
Submissions from 2001
Truncated Forms of the Dual Function Human ASCT2 Neutral Amino Acid Transporter/Retroviral Receptor Are Translationally Initiated at Multiple Alternative CUG and GUG Codons, Chetankumar S. Tailor, Mariana Marin, Ali Nouri, Michael Kavanaugh, and David Kabat
Submissions from 2000
Arginine 447 Plays a Pivotal Role in Substrate Interactions in a Neuronal Glutamate Transporter, Annie Bendahan, Ayelet Armon, Navid Madani, Michael Kavanaugh, and Baruch I. Kanner
Pentameric assembly of a neuronal glutamate transporter, Sepehr Eskandari, Michael Kreman, Michael Kavanaugh, Ernest M. Wright, and Guido A. Zampighi
Isolation of Current Components and Partial Reaction Cycles in the Glial Glutamate Transporter EAAT2, Thomas S. Otis and Michael Kavanaugh
Submissions from 1999
A Critical Site in the Core of the CCR5 Chemokine Receptor Required for Binding and Infectivity of Human Immunodeficiency Virus Type 1, Salvatore J. Siciliano, Shawn E. Kuhmann, Youmin Weng, Navid Madani, Martin S. Springer, Janet E. Lineberger, Renee Danzeisen, Michael D. Miller, Michael Kavanaugh, Julie A. DeMartino, and David Kabat
Submissions from 1998
Excitatory Amino Acid Transporters of the Salamander Retina: Identification, Localization, and Function, Scott Eliasof, Jeffrey L. Arriza, Barbara H. Leighton, Michael Kavanaugh, and Susan G. Amara
Neurotransmitter transport: Models in flux, Michael Kavanaugh
gp120 envelope glycoproteins of human immunodeficiency viruses competitively antagonize signaling by coreceptors CXCR4 and CCR5, Navid Madani, Susan L. Kozak, Michael Kavanaugh, and David Kabat
Arachidonic Acid Activates a Proton Current in the Rat Glutamate Transporter EAAT4, Anastassios V. Tzingounis, Chien-Liang Lin, Jeffrey D. Rothstein, and Michael Kavanaugh
Macroscopic and Microscopic Properties of a Cloned Glutamate Transporter/Chloride Channel, Jacques I. Wadiche and Michael Kavanaugh
Cysteine Scanning of the Surroundings of an Alkali-Ion Binding Site of the Glutamate Transporter GLT-1 Reveals a Conformationally Sensitive Residue, Ruth Zarbiv, Myriam Grunewald, Michael Kavanaugh, and Baruch I. Kanner
Molecular determinant of ion selectivity of a (Na+ + K+)-coupled rat brain glutamate transporter, Yumin Zhang, Annie Bendahan, Ruth Zarbiv, Michael Kavanaugh, and Baruch I. Kanner
Submissions from 1997
Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance, Jeffrey L. Arriza, Scott Eliasof, Michael Kavanaugh, and Susan G. Amara
Tyrosine 140 of the γ-Aminobutyric Acid Transporter GAT-1 Plays a Critical Role in Neurotransmitter Recognition, Yona Bismuth, Michael Kavanaugh, and Baruch I. Kanner
Mutation of an Amino Acid Residue Influencing Potassium Coupling in the Glutamate Transporter GLT-1 Induces Obligate Exchange, Michael Kavanaugh, Annie Bendahan, Noa Zerangue, Yumin Zhang, and Baruch I. Kanner
Aspartate 19 and Glutamate 121 Are Critical for Transport Function of the myo-Inositol/H+ symporter from Leishmania donovani, Andreas Seyfang, Michael Kavanaugh, and Scott M. Landfear
Multiple Ionic Conductances of the Human Dopamine Transporter: The Actions of Dopamine and Psychostimulants, Mark S. Sonders, Si-Jia Zhu, Nancy R. Zahniser, Michael Kavanaugh, and Susan G. Amara
Submissions from 1996
Kinetics and Stoichiometry of a Proton/myo-Inositol Cotransporter, Elizabeth M. Klamo, Mark E. Drew, Scott M. Landfear, and Michael Kavanaugh
ASCT-1 Is a Neutral Amino Acid Exchanger with Chloride Channel Activity, Noa Zerangue and Michael Kavanaugh
Submissions from 1995
A Family of Putative Receptor-Adenylate Cyclases from Leishmania donovani, Marco A. Sanchez, David Zeoli, Elizabeth M. Klamo, Michael Kavanaugh, and Scott M. Landfear
Constitutive Ion Fluxes and Substrate Binding Domains of Human Glutamate Transporters, Robert J. Vandenberg, Jeffrey L. Arriza, Susan G. Amara, and Michael Kavanaugh
Differential Modulation of Human Glutamate Transporter Subtypes by Arachidonic Acid, Noa Zerangue, Jeffrey L. Arriza, Susan G. Amara, and Michael Kavanaugh
Submissions from 1994
Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex, Jeffrey L. Arriza, Wendy A. Fairman, Jacques I. Wadiche, Geoffrey H. Murdoch, Michael Kavanaugh, and Susan G. Amara
Cell-surface receptors for gibbon ape leukemia virus and amphotropic murine retrovirus are inducible sodium-dependent phosphate symporters, Michael Kavanaugh, Daniel G. Miller, Weibin Zhang, Wendy Law, Susan L. Kozak, David Kabat, and A. Dusty Miller
Control of cationic amino acid transport and retroviral receptor functions in a membrane protein family, Michael Kavanaugh, Hao Wang, Zheng Zhang, Weibin Zhang, Yan-Na Wu, Esther Dechant, R. Alan North, and David Kabat
Functional expression of two glucose transporter isoforms from the parasitic protozoan Leishmania enriettii, Chris K. Langford, Brian M. Little, Michael Kavanaugh, and Scott M. Landfear
Cloning of the cellular receptor for amphotropic murine retroviruses reveals homology to that for gibbon ape leukemia virus, Daniel G. Miller, Robert H. Edwards, and A. Dusty Miller
Submissions from 1993
Cloning and expression of a human neutral amino acid transporter with structural similarity to the glutamate transporter gene family, Jeffrey L. Arriza, Michael Kavanaugh, Wendy A. Fairman, Yan-Na Wu, Geoffrey H. Murdoch, R. Alan North, and Susan G. Amara
Submissions from 1992
Cooperative interactions among subunits of a voltage-dependent potassium channel. Evidence from expression of concatenated cDNAs, Raymond S. Hurst, Michael Kavanaugh, Jerrel Yakel, John P. Adelman, and R. Alan North
Electrogenic uptake of gamma-aminobutyric acid by a cloned transporter expressed in Xenopus oocytes, Michael Kavanaugh, Jeffrey L. Arriza, R. Alan North, and Susan G. Amara
Effects of ecotropic murine retroviruses on the dual-function cell surface receptor/basic amino acid transporter, Hao Wang, Esther Dechant, Michael Kavanaugh, R. Alan North, and David Kabat
Submissions from 1991
Interaction between tetraethylammonium and amino acid residues in the pore of cloned voltage-dependent potassium channels, Michael Kavanaugh, Michael D. Varnum, Peregrine B. Osborne, MacDonald J. Christie, Andreas E. Busch, John P. Adelman, and R. Alan North
Submissions from 1989
Structure and function of human hemoglobin covalently labeled with periodate-oxidized adenosine triphosphate, Michael Kavanaugh, Max F. Perutz, Giulio Fermi, Daniel T. Shih, and Richard T. Jones
Submissions from 1988
Identification of the binding subunit of the sigma-type opiate receptor by photoaffinity labeling with 1-(4-azido-2-methyl[6-3H]phenyl)-3-(2-methyl[4,6-3H]phenyl)guanidine, Michael Kavanaugh, Barbara C. Tester, Michael W. Scherz, John F. W. Keana, and Eckard Weber